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Although a decline in HBV viral load correlates with response, no threshold HBV viral load has been established that clearly defines a virological response.

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The DNA in the viral cell needs to be replicated in order to reproduce and increase infection.

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Caution should be exercised when administering lamivudine tablets to any patient with known risk factors for liver disease; however, cases also have been reported in patients with no known risk factors.

The daily steady-state area under the curve for a dose of 100 mg was the same whether the dose was given once daily or twice daily (at 12-hour intervals) and was correlated with maximal viral suppression (Johnson M: personal communication).

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CD) is a chronic relapsing inflammatory bowel disease (IBD) associated with marked abnormalities in intestinal motility suggesting that impairment in the enteric nervous system (ENS) underlines some of the functional abnormalities observed in patients with IBD.

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Surgical intervention is the primary treatment for acute cholecystitis that fails medical management, or if obstructive jaundice or gallstone pancreatitis exists, or if peritonitis is suspected.

The major aims of this study are to evaluate the long-term efficacy and safety of lamivudine therapy and the possibility of stopping therapy in a cohort of patients with chronic hepatitis B who have a maintained response to treatment.

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Natural history of HIV infection in the era of combination antiretroviral therapy".

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Cardiac monitoring in an in-patient setting for the first 48 hours of coadministration is recommended, after which outpatient or self-monitoring of the heart rate should occur on a daily basis through at least the first 2 weeks of treatment.

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The adverse effects are negligible, although a transient elevation of aminotransferases can be noticed shortly after starting treatment.

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PCP) An opportunistic infection caused by a fungus that is a major cause of death in patients with late-stage AIDS.


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Figure 3 Time to Safety End Point.

This is accounted for by the possible differences in their inactive ingredients such as color and flavor additives, and by the copyright and trademark regulations that does not allow for exact copies of the existing brand-name products.

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It is important to note that bacterial infections are frequent, especially in decompensated cirrhotics, exacerbating hepatic dysfunction, encephalopathy and portal hypertension and underlining the need for vigilance and rigorous antibiotic treatment in cirrhosis.

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The cells are then cultured for mass production of the protein, which can then be exposed to various treatment candidates and evaluated with "rapid screening" technologies.

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After intracellular conversion to its active form (lamivudine-5-triphosphate), inhibits viral DNA synthesis by inhibiting the enzyme reverse transcriptase.

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